Enterprise systems provide integrated information for all activities in an organization. These systems serve as a vital asset to any organization and hence it becomes mandatory to ensure their security. Information security combines systems, operations and internal controls to ensure the availability, integrity and confidentiality of data and operational procedures in an organization. In the present scenario these services are offered on the cloud mainly to reduce inherent risk associated with the traditional enterprise systems. Cloud computing represents a significant shift in the way that IT resources are managed, operated, and consumed. This change exposes several benefits to enterprises, promoting greater IT efficiency and agility. This paper is intended to suggest a security framework of enterprise systems on cloud.